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Antihistamines can block the full benefits of exercise
POSTED 28 Apr 2021 . BY Tom Walker
Many people take antihistamines prior to exercising outdoors Credit: Shutterstock/Maridav
Taking antihistamines prior to exercise can prevent the body from getting the full benefit of exercise.

That's the finding of a new study, which found antihistamines reduce normal increases in blood flow to the muscles by 35 per cent during exercise.

Conducted by Ghent University and the University of Copenhagen and published in the Science Advances journal, the study also found that antihistamines decreased aerobic capacity, blocked the improvements that exercise has on circulation and the body's ability to tolerate glucose.

Antihistamines are a common drug used by hayfever sufferers – and many take some before exercising outdoors.

Senior author on the study, sport scientist Professor Dr Wim Derave, told HCM: "Exercise training induces health-promoting adaptations to multiple organ systems, orchestrated by an interplay between various exercise factors and signaling events.

"In the present study, we show that histamine H1/H2 signaling is an essential transducer of the adaptive exercise training response, with broad clinical relevance: aerobic capacity, glycemic control, and vascular function.

"These detrimental effects of H1/H2 blockade on functional outcomes were caused by impaired adaptations in key regulatory proteins, illustrating the integrative role of H1/H2 receptors in mediating exercise responses.

"One potential functional cause of the blunted training adaptations with histamine receptor blockade is a substantially reduced post-exercise muscle perfusion."

To read the full research paper, titled Histamine H1 and H2 receptors are essential transducers of the integrative exercise training response in humans, click here
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Jobs   News   Products   Magazine
NEWS
Antihistamines can block the full benefits of exercise
POSTED 28 Apr 2021 . BY Tom Walker
Many people take antihistamines prior to exercising outdoors Credit: Shutterstock/Maridav
Taking antihistamines prior to exercise can prevent the body from getting the full benefit of exercise.

That's the finding of a new study, which found antihistamines reduce normal increases in blood flow to the muscles by 35 per cent during exercise.

Conducted by Ghent University and the University of Copenhagen and published in the Science Advances journal, the study also found that antihistamines decreased aerobic capacity, blocked the improvements that exercise has on circulation and the body's ability to tolerate glucose.

Antihistamines are a common drug used by hayfever sufferers – and many take some before exercising outdoors.

Senior author on the study, sport scientist Professor Dr Wim Derave, told HCM: "Exercise training induces health-promoting adaptations to multiple organ systems, orchestrated by an interplay between various exercise factors and signaling events.

"In the present study, we show that histamine H1/H2 signaling is an essential transducer of the adaptive exercise training response, with broad clinical relevance: aerobic capacity, glycemic control, and vascular function.

"These detrimental effects of H1/H2 blockade on functional outcomes were caused by impaired adaptations in key regulatory proteins, illustrating the integrative role of H1/H2 receptors in mediating exercise responses.

"One potential functional cause of the blunted training adaptations with histamine receptor blockade is a substantially reduced post-exercise muscle perfusion."

To read the full research paper, titled Histamine H1 and H2 receptors are essential transducers of the integrative exercise training response in humans, click here
RELATED STORIES
Exercise benefits cancer patients, studies show


Exercise is likely to benefit breast and prostate cancer patients, both during and after treatment, according to studies presented at a US cancer research conference.
New drugs dramatically increase healthy lifespan: research


A new class of drugs has been identified that dramatically slows the ageing process, alleviating symptoms of frailty, improving cardiac function and extending a healthy lifespan, according to a recent study.
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Jubilation as group exercise reopens in most of the UK
Indoor group exercise can recommence in England and Scotland today (17 May), as part of the easing of lockdown measures.
54 per cent of public sector health clubs and leisure centres at risk of closure without government help
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iFit: your readymade omnichannel fitness solution
With gyms and leisure centres in England reopened, and the rest of the UK due to shortly follow suit, the time for being theoretical is over. [more...]
+ More featured suppliers  
COMPANY PROFILES
TRIB3 International Ltd

A world class experience to challenge every client. Affordable luxury brand with award winning des [more...]
+ More profiles  
CATALOGUE GALLERY
+ More catalogues  

VIDEO GALLERY

PENDEX | Simply Ingenious
It trains humans better than humans train humans. Find out more...
+ More videos  

DIRECTORY
+ More directory  
DIARY

 

17-20 May 2021

Hot Springs Connection Conference

Quinns Hot Springs Resort, Paradise, United States
23-26 May 2021

Global Beauty & Wellness Exchange

Montage Deer Valley, Park City, United States
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ABOUT LEISURE MEDIA
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PRINT SUBSCRIPTIONS
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