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Brown fat 'talks back' to the brain via the nervous system: study
POSTED 02 Apr 2015 . BY Helen Andrews
The study shows a feedback loop between brown fat tissue and the brain via the nervous system – which could be useful in the fight against obesity Credit: Shutterstock / Mopic
Brown fat tissue - the body’s ‘good fat’ - serves as an organ which communicates with the brain through sensory nerves to inform how much fat we have and how much we’ve lost while the brown fat is generating heat, a study has found.

Pharmaceutical companies are trying to target brown fat and activate it more because it burns calories to help generate heat for our bodies and expend energy. White fat, however, stores energy for later and too much of it can increase the risk for health issues such as obesity, diabetes and heart disease.

Researchers from Georgia State University found that brown fat tissue ‘talks back’ to the brain by activating sensory nerves. The sensory nerves from brown fat increased their activity in response to direct chemical activation and heat generation, according to the results that were published in The Journal of Neuroscience.

Johnny Garretson, study author and doctoral student in the Neuroscience Institute and Center for Obesity Reversal at Georgia State, said: “This is the first time that the function of sensory nerves from brown fat has been examined. Brown fat is an active organ that’s relatively important for metabolism and we’ve found a new pathway of its communication.”

“There is evidence that people with more brown fat have a better metabolism, lower instances of type two diabetes and are trimmer,” continued Garretson. “Knowing how to increase the amount of brown fat activity or increase the brown fat – that’s the future of trying to figure out yet another way to try and lose weight effectively and quickly.”

“As brown fat gets hotter and starts to generate heat – doing good things for our body – it increases our metabolism and helps us burn white fat,” added Garretson. “As it’s getting hotter, the lab found that it tells the brain it’s getting hotter. We think this is some type of feedback, like a thermostat, and as it gets hotter, it probably controls how the brain is talking back to it.”

This study therefore shows a feedback loop between brown fat tissue and the brain via the nervous system – which could become a useful tool in the fight against obesity.

Read more:

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NEWS
Brown fat 'talks back' to the brain via the nervous system: study
POSTED 02 Apr 2015 . BY Helen Andrews
The study shows a feedback loop between brown fat tissue and the brain via the nervous system – which could be useful in the fight against obesity Credit: Shutterstock / Mopic
Brown fat tissue - the body’s ‘good fat’ - serves as an organ which communicates with the brain through sensory nerves to inform how much fat we have and how much we’ve lost while the brown fat is generating heat, a study has found.

Pharmaceutical companies are trying to target brown fat and activate it more because it burns calories to help generate heat for our bodies and expend energy. White fat, however, stores energy for later and too much of it can increase the risk for health issues such as obesity, diabetes and heart disease.

Researchers from Georgia State University found that brown fat tissue ‘talks back’ to the brain by activating sensory nerves. The sensory nerves from brown fat increased their activity in response to direct chemical activation and heat generation, according to the results that were published in The Journal of Neuroscience.

Johnny Garretson, study author and doctoral student in the Neuroscience Institute and Center for Obesity Reversal at Georgia State, said: “This is the first time that the function of sensory nerves from brown fat has been examined. Brown fat is an active organ that’s relatively important for metabolism and we’ve found a new pathway of its communication.”

“There is evidence that people with more brown fat have a better metabolism, lower instances of type two diabetes and are trimmer,” continued Garretson. “Knowing how to increase the amount of brown fat activity or increase the brown fat – that’s the future of trying to figure out yet another way to try and lose weight effectively and quickly.”

“As brown fat gets hotter and starts to generate heat – doing good things for our body – it increases our metabolism and helps us burn white fat,” added Garretson. “As it’s getting hotter, the lab found that it tells the brain it’s getting hotter. We think this is some type of feedback, like a thermostat, and as it gets hotter, it probably controls how the brain is talking back to it.”

This study therefore shows a feedback loop between brown fat tissue and the brain via the nervous system – which could become a useful tool in the fight against obesity.

Read more:

Exercise has the power to change our DNA: study
Studies suggest exercise and diet may not be enough to tackle obesity
Weekend lie-ins driving obesity: study
Inactivity twice as deadly as obesity, finds landmark study
EU courts rule obesity can be classed as a disability
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High fat diet alters behaviour and causes brain inflammation: study


A high fat diet, which changes the mix of bacteria in the gut, alters behaviour and produces signs of brain inflammation – even in the absence of obesity, according to a study.
Obesity perceptions can influence a person's sense of smell: study


Looking at images associated with overweight or obese people can influence a person’s sense of smell, according to a study. The more negatively someone feels towards the obese image, the worse he or she will tend to rate a particular scent.
Obesity brings 40 per cent higher cancer risk for women: study


Health experts are urging obese women to adopt healthier lifestyles, following research suggesting they have a 40 per cent greater risk of weight-related cancer.
Experimental drug increases metabolic rate: study


An experimental drug has been found to speed up metabolism and burn off fat cells, according to a study conducted on hundreds of mice by the Houston Methodist Research Institute, US.
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